After heating the mixture for 5 minutes, gravity filter what is in the 25 mL Erlenmeyer flask through filter paper. Weigh the weigh boat with sample inside and record the mass of the crude product formed.
Place the 25 mL Erlenmeyer flask containing the product and ethyl acetate directly on the hot plate at 50 degrees Celsius.
Invert the capillary tube and stick the open end of the capillary tube in the densest part of the crystal sample. The aspirin product that was collected still contained some impurities. Also, set up an ice bath for the mixture in the Erlenmeyer flask as well as a second ice bath for the mL beaker while waiting for the mixture in the Erlenmeyer flask to heat.
This led us to believe that our purified aspirin product did not contain any phenol group and was pure aspirin. The phenol test was to test the purity of the aspirin product that was created during the experiment. This low percent yield of purified aspirin product was due to a few different factors.
Next perform the phenol test. Phenols form a highly colored complex with iron III chloride that can range from a pale to dark purple depending on the concentration of the phenol group present in the solution. In this experiment aspirin was synthesized from salicylic acid and acetic anhydride.
Due to apparent wetness of the product it is estimated that half of the mass is due to moisture. The solid aspirin product was trapped by the filter and the liquid was drawn through the funnel into the flask below it by a vacuum. Next, place a few crystals of the crude product in a test tube labeled A and put to the side for later use.
Put what goes through the filter paper back in the 25 mL Erlenmeyer flask and add petroleum ether drop by drop until crystals begin to form. A pure compound has a specific range in which it melts and it is normally a fairly small range.
As early as BC ancient cultures such as Greek, Roman, Egyptian, and Chinese found that extracts from plants such as willow bark, meadowsweet, and myrtle possessed the ability to alleviate fever, pain, and inflammation.
The third factor that caused a low percent yield of our purified product was that when we vacuum filtered our purified product, some of our purified product fell through the filter and into the side arm flask.
Scratch the bottom of the Erlenmeyer flask with a glass stirring rod with strong force. Heat the mixture using a water bath for 10 minutes. In this experiment aspirin, also known as acetylsalicylic acid, was synthesized from salicylic acid and acetic anhydride.
Different safety techniques were taken into consideration to ensure the lab was correctly executed. Record the color observations.Experiment 22 Synthesis of Aspirin and Oil of Wintergreen GOALS: salicylic acid.
One of the esters, acetylsalicylic acid, is aspirin, the common analgesic. We will synthesize aspirin by mixing salicylic acid with acetic anhydride. The second ester product is oil of wintergreen, or LABORATORY OBSERVATIONS AND DATA.
active component, salicylic acid (SA), can, however, cause stomach upset because its acidity (pK a = ) can be higher than the pH of the human stomach (pH ~ 4 after digestion is complete).
Figure 1. Salicylic Acid Salicylic acid is a diprotic organic acid with two acidic functional groups: a carboxylic acid and a phenol. 1.
Weigh g ( mol) of salicylic acid in a mL Erlenmeyer flask. Using this quantity of salicylic acid to calculate the theoretical yield of aspirin. Record the weigh on the report sheet.
2. Carefully add 6 mL ( mol) of acetic anhydride to the flask. (CAREFUL! Acetic anhydride is irritating to the skin and eyes.) 3. CHEM Lab Manual /04 Experiment 10 51 Experiment 10 Fischer Esterification: An ester from a carboxylic acid and an alcohol Emil Fischer ().
After discovering phenylhydrazine as a graduate student, he is best known for all. (aspirin), an acetic acid ester of salicylic acid, can be taken orally with few complications, the body eventually removes the acetyl group to produce salicylic acid which is a pain reliever and anti-inflammatory agent.
Ester Preparation Lab Introduction: An ester is an organic compound which is created from a reaction between an acid and an alcohol, usually with the loss of water.Download